RESEARCH RESULTS

研究業績

2013年 教室業績
  1. Oishi A, Yamashiro K, Tsujikawa A, Ooto S, Tamura H, Nakata I, Miyake M, Yoshimura N. Long-term effect of intravitreal injection of anti-VEGF agent for visual acuity and chorioretinal atrophy progression in myopic choroidal neovascularization. Graefe’s Arch Clin Exp Ophthalmol. 2013;251:1-7.
  2. Muraoka Y, Tsujikawa A, Murakami T, Ogino K, Kumagai K, Miyamoto K, Uji A, Yoshimura N. Morphologic and functional changes in retinal vessels associated with branch retinal vein occlusion. Ophthalmology. 2013;120:91-99.
  3. Hirashima T, Hangai M, Nukada M, Nakano N, Morooka S, Akagi T, Nonaka A, Yoshimura N. Frequency-doubling technology and retinal measurements with spectral-domain optical coherence tomography in preperimetric glaucoma. Graefe’s Arch Clin Exp Ophthalmol. 2013;251:129-137.
  4. Yoshikawa M, Murakami T, Nishijima K, Uji A, Ogino K, Horii T, Yoshimura N. Macular migration toward the optic disc after inner limiting membrane peeling for diabetic macular edema. Invest Ophthalmol Vis Sci. 2013;54:629-635.
  5. Ota T, Tsujikawa A, Murakami T, Ogino K, Muraoka Y, Kumagai K, Akagi-Kurashige Y, Miyamoto K, Yoshimura N. Subfoveal serous retinal detachment associated with extramacular branch retinal vein occlusion. Clin Ophthalmol. 2013;7:237-241.
  6. Ueda-Arakawa N, Ooto S, Nakata I, Yamashiro K, Tsujikawa A, Oishi A, Yoshimura N. Prevalence and genomic association of reticular pseudodrusen in age-related macular degeneration. Am J Ophthalmol. 2013;155:260-269.
  7. Ellabban AA, Tsujikawa A, Matsumoto A, Yamashiro K, Oishi A, Ooto S, Nakata I, Akagi-Kurashige Y, Miyake M, Elnahas HS, Radwan TM, Zaky KA, Yoshimura N. Three-dimensional tomographic features of dome-shaped macula by swept-source optical coherence tomography. Am J Ophthalmol. 2013;155:320-328.
  8. Hata M, Miyamoto K, Nakagawa S, Horii T, Yoshimura N. Horizontal deviation as diagnostic and prognostic values in isolated fourth nerve palsy. Br J Ophthalmol. 2013;97:180-183.
  9. Oishi A, Shimozono M, Mandai M, Hata M, Nishida A, Kurimoto Y. Recovery of photoreceptor outer segments after anti-VEGF therapy for age-related maculardegeneration. Graefe’s Arch Clin Exp Ophthalmol. 2013;251:435-440.
  10. Ito S, Miyamoto N, Ishida K, Kurimoto Y. Association between external limiting membrane status and visual acuity in diabetic macular oedema. Br J Ophthalmol.2013;97:228-232.
  11. Hata M, Oishi A, Shimozono M, Mandai M, Nishida A, Kurimoto Y. Early changes in foveal thickness in eyes with central serous chorioretinopathy. Retina. 2013;33:296-301.
  12. Chihara T, Kita M. New type of antidrying lens for vitreous surgery with a noncontact wide-angle viewing system. Clin Ophthalmol. 2013;7:353-355.
  13. Ueda-Arakawa N, Ooto S, Tsujikawa A, Yamashiro K, Oishi A, Yoshimura N. Sensitivity and specificity of detecting reticular pseudodrusen in multimodal imaging in Japanese patients. Retina. 2013;33:490-497.
  14. Wakazono T, Ooto S, Hangai M, Yoshimura N. Photoreceptor outer segment abnormalities and retinal sensitivity in acute zonal occult outer retinopathy. Retina.2013;33:642-648.
  15. Kameda T, Inoue T, Inatani M, Tanihara H; Japanese Phaco-Goniosynechialysis Multicenter Study Group. Long-term efficacy of goniosynechialysis combined with phacoemulsification for primary angle closure. Graefe’s Arch Clin Exp Ophthalmol.2013;251:825-830.
  16. Kita M, Fujii Y, Kawagoe N, Hama S. Scleral buckling with a noncontact wideangle viewing system in the management of retinal detachment with undetected retinal break: a case report. Clin Ophthalmol. 2013;7:587-589.
  17. Hata M, Miyamoto K, Ogino K, Sumiyoshi S, Yoshimura N. Conjunctival extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the fornix: do not overlook conjunctival lymphomas. Clin Ophthalmol. 2013;7:663-666.
  18. Nukada K, Hangai M, Ooto S, Yoshikawa M, Yoshimura N. Tomographic features of macula after successful macular hole surgery. Invest Ophthalmol Vis Sci.2013;54:2417-2428.
  19. Nomura T, Kayama T, Okamura E, Ogino K, Uji A, Yoshimura N, Kikuchi T,Fujisawa A, Tanioka M, Miyachi Y, Kabashima K. Severe atopic dermatitis accompanied by autoimmune retinopathy. Eur J Dermatol. 2013;23:263-264.
  20. Hirasawa H, Araie M, Tomidokoro A, Saito H, Iwase A, Ohkubo S, Sugiyama K,Ootani T, Kishi S, Matsushita K, Maeda N, Hangai M, Yoshimura N. Reproducibility of thickness measurements of macular inner retinal layers using SD-OCT with or without correction of ocular rotation. Invest Ophthalmol Vis Sci. 2013;54:2562-2570.
  21. Hata M, Miyamoto K, Oishi A, Yoshimura N. Case of simultaneous bilateral anterior ischemic optic neuropathy associated with Takayasu disease. Can J Ophthalmol. 2013;48:e33-35.
  22. Ito H, Horii T, Nishijima K, Sakamoto A, Ota M, Murakami T, Yoshimura N. Association between fluorescein leakage and optical coherence tomographic characteristics of microaneurysms in diabetic retinopathy. Retina. 2013;33:732-739.
  23. Nakagawa S, Yamashiro K, Tsujikawa A, Otani A, Tamura H, Ooto S, Yoshimura N. The time course changes of choroidal neovascularization in angioid streaks. Retina.2013;33:825-833.
  24. Nakata I, Tsujikawa A, Yamashiro K, Otani A, Ooto S, Akagi-Kurashige Y, Ueda-Arakawa N, Iwama D, Yoshimura N. Two-year outcome of photodynamic therapy combined with intravitreal injection of bevacizumab and triamcinolone acetonide for polypoidal choroidal vasculopathy. Graefe’s Arch Clin Exp Ophthalmol.2013;251:1073-1080.
  25. Takayama K, Ooto S, Hangai M, Ueda-Arakawa N, Yoshida S, Akagi T, Ikeda HO, Nonaka A, Hanebuchi M, Inoue T, Yoshimura N. High-resolution imaging of retinal nerve fiber bundles in glaucoma using adaptive optics scanning laser ophthalmoscopy. Am J Ophthalmol. 2013;155:870-881.
  26. Akagi T, Hangai M, Kimura Y, Ikeda HO, Nonaka A, Matsumoto A, Akiba M, Yoshimura N. Peripapillary scleral deformation and retinal nerve fiber damage in high myopia assessed with swept-source optical coherence tomography. Am J Ophthalmol.2013;155:927-936.
  27. Ogino K, Otani A, Oishi A, Kurimoto M, Sekiya T, Yoshimura N. Concentric division of 10° visual field tests in retinitis pigmentosa. Jpn J Ophthalmol. 2013;57:268-274.
  28. Muraoka Y, Tsujikawa A, Murakami T, Ogino K, Miyamoto K, Yoshimura N. Branch retinal vein occlusion-associated subretinal hemorrhage. Jpn J Ophthalmol.2013;57:275-282.
  29. Ogino K, Tsujikawa A, Yamashiro K, Ooto S, Oishi A, Nakata I, Miyake M, Yoshimura N. Intravitreal injection of ranibizumab for recovery of macular function in eyes with subfoveal polypoidal choroidal vasculopathy. Invest Ophthalmol Vis Sci.2013;54:3771-3779.
  30. Oishi A, Ogino K, Nakagawa S, Makiyama Y, Kurimoto M, Otani A, Yoshimura N.Longitudinal analysis of the peripapillary retinal nerve fiber layer thinning in patients with retinitis pigmentosa. Eye (Lond). 2013;27:597-604.
  31. Miki A, Honda S, Kojima H, Nishizaki M, Nagai T, Fujihara M, Uenishi M, Kita M, Kurimoto Y, Negi A; Hyogo Macular Disease Study Group. Visual outcome of photodynamic therapy for typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy over 5 years of follow-up. Jpn J Ophthalmol.2013;57:301-307.
  32. Miyake M, Yamashiro K, Nakanishi H, Nakata I, Akagi-Kurashige Y, Tsujikawa A, Moriyama M, Ohno-Matsui K, Mochizuki M, Yamada R, Matsuda F, Yoshimura N. Insulin-like growth factor 1 is not associated with high myopia in a large Japanese cohort. Mol Vis. 2013;19:1074-1081.
  33. Yokota S, Ooto S, Hangai M, Takayama K, Ueda-Arakawa N, Yoshihara Y,Hanebuchi M, Yoshimura N. Objective assessment of foveal cone loss ratio in surgically closed macular holes using adaptive optics scanning laser ophthalmoscopy.PLoS One. 2013;8:e63786.
  34. Iida Y, Hangai M, Yoshikawa M, Ooto S, Yoshimura N. Local biometric features and visual prognosis after surgery for treatment of myopic foveoschisis. Retina.2013;33:1179-1187.
  35. Ooto S, Hangai M, Takayama K, Ueda-Arakawa N, Tsujikawa A, Yamashiro K, Oishi A, Hanebuchi M, Yoshimura N. Comparison of cone pathologic changes in idiopathic macular telangiectasia types 1 and 2 using adaptive optics scanning laser Ophthalmoscopy. Am J Ophthalmol. 2013;155:1045-1057.
  36. Takahashi A, Ooto S, Yoshimura N. High-penetration optical coherence tomography and enhanced depth imaging in presumed retinal pigment epithelial hamartoma. Retinal Cases and Brief Reports. 2013;7:179-182.
  37. Ozeki-Jingami Y, Ooto S, Hangai M, Tsujikawa A, Yoshimura N. Features and surgical outcome of retinal nerve fiber layer alterations associated with epiretinal membrane. Retinal Cases and Brief Reports. 2013;7:198-203.
  38. Awai-Kasaoka N, Inoue T, Kameda T, Fujimoto T, Inoue-Mochita M, Tanihara H. Oxidative stress response signaling pathways in trabecular meshwork cells and their effects on cell viability. Mol Vis. 2013;19:1332-1340.
  39. Miyake M, Yamashiro K, Nakanishi H, Nakata I, Akagi-Kurashige Y, Kumagai K, Oishi M, Tsujikawa A, Moriyama M, Ohno-Matsui K, Mochizuki M, Yoshimura N. Evaluation of pigment epithelium-derived factor and complement factor I polymorphisms as a cause of choroidal neovascularization in highly myopic eyes. Invest Ophthalmol Vis Sci. 2013;54:4208-4212.
  40. Arichika S, Uji A, Hangai M, Ooto S, Yoshimura N. Noninvasive and direct monitoring of erythrocyte aggregates in human retinal microvasculature using adaptive optics scanning laser ophthalmoscopy. Invest Ophthalmol Vis Sci. 2013;54:4394-4402.
  41. Mayama C, Saito H, Hirasawa H, Konno S, Tomidokoro A, Araie M, Iwase A, Ohkubo S, Sugiyama K, Otani T, Kishi S, Matsushita K, Maeda N, Hangai M, Yoshimura N. Circle-and grid-wise analyses of peripapillary nerve fiber layers by spectral domain optical coherence tomography in early-stage glaucoma. Invest Ophthalmol Vis Sci. 2013;54:4519-4526.
  42. Takayama K, Hangai M, Kimura Y, Morooka S, Nukada M, Akagi T, Ikeda HO, Matsumoto A, Yoshimura N. Three-dimensional imaging of lamina cribrosa defects in glaucoma using swept-source optical coherence tomography. Invest Ophthalmol Vis Sci. 2013;54:4798-4807.
  43. Kuriyama S, Hayashi H, Jingami Y, Kuramoto N, Akita J, Matsumoto M. Efficacy of inverted internal limiting membrane flap technique for the treatment of macular hole in high myopia. Am J Ophthalmol. 2013;156:125-131.
  44. Eye Care Comparative Effectiveness Research Team (ECCERT), Hiratsuka Y, Yamada M, Akune Y, Murakami A, Okada AA, Yamashita H, Ohashi Y, Yamagishi N, Tamura H, Fukuhara S, Takura T. Cost-utility analysis of cataract surgery in Japan: a probabilistic Markov modeling study. Jpn J Ophthalmol. 2013;57:391-401.
  45. Lee J, Hangai M, Kimura Y, Takayama K, Kee C, Yoshimura N. Measurement of macular ganglion cell layer and circumpapillary retinal nerve fiber layer to detect paracentral scotoma in early glaucoma. Graefe’s Arch Clin Exp Ophthalmol. 2013;251:2003-2012.
  46. Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, Macgregor S, Verhoeven VJ, Barathi VA, Liao J, Hysi PG, Bailey-Wilson JE, St Pourcain B, Kemp JP, McMahon G, Timpson NJ, Evans DM, Montgomery GW, Mishra A, Wang YX, Wang JJ, Rochtchina E, Polasek O, Wright AF, Amin N, van Leeuwen EM, Wilson JF, Pennell CE, van Duijn CM, de Jong PT, Vingerling JR, Zhou X, Chen P, Li R, Tay WT, Zheng Y, Chew M; Consortium for Refractive Error and Myopia, Burdon KP, Craig JE, Iyengar SK, Igo RP Jr, Lass JH Jr; The Fuchs’ Genetics Multi-Center Study Group, Chew EY, Haller T, Mihailov E, Metspalu A, Wedenoja J, Simpson CL, Wojciechowski R, Höhn R, Mirshahi A, Zeller T, Pfeiffer N, Lackner KJ; Wellcome Trust Case Control Consortium 2, Bettecken T, Meitinger T, Oexle K, Pirastu M, Portas L, Nag A, Williams KM, Yonova-Doing E, Klein R, Klein BE, Hosseini SM, Paterson AD; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions, and Complications Research Group, Makela KM, Lehtimaki T, Kahonen M, Raitakari O, Yoshimura N, Matsuda F, Chen LJ, Pang CP, Yip SP, Yap MK, Meguro A, Mizuki N, Inoko H, Foster PJ, Zhao JH, Vithana E, Tai ES, Fan Q, Xu L, Campbell H, Fleck B, Rudan I, Aung T, Hofman A, Uitterlinden AG, Bencic G, Khor CC, Forward H, Pärssinen O, Mitchell P, Rivadeneira F, Hewitt AW, Williams C, Oostra BA, Teo YY, Hammond CJ, Stambolian D, Mackey DA, Klaver CC, Wong TY,Saw SM, Baird PN. Nine loci for ocular axial length identified through Genome-wide association studies, including shared loci with refractive error. Am J Hum Genet. 2013;93:264-277.
  47. Makiyama Y, Kikuchi T, Otani A, Oishi A, Guo C, Nakagawa S, Ogino K, Kojima H, Kurimoto M, Yoshimura N. Clinical and immunological characterization of paraneoplastic retinopathy. Invest Ophthalmol Vis Sci. 2013;54:5424-5431.
  48. Murakami T, Yoshimura N. Structural changes in individual retinal layers in diabetic macular edema. J Diabetes Res. 2013;2013:920713.
  49. Nakano N, Hangai M, Noma H, Nukada M, Mori S, Morooka S, Takayama K, Kimura Y, Ikeda HO, Akagi T, Yoshimura N. Macular imaging in highly myopic eyes with and without glaucoma. Am J Ophthalmol. 2013;156:511-523.
  50. Nakata I, Yamashiro K, Kawaguchi T, Gotoh N, Nakanishi H, Akagi-Kurashige Y, Miyake M, Tsujikawa A, Oishi A, Saito M, Iida T, Study Group N, Yamada R, Matsuda F, Yoshimura N. Association between the cholesteryl ester transfer protein gene and polypoidal choroidal vasculopathy. Invest Ophthalmol Vis Sci. 2013;54:6068-6073.
  51. Oishi A, Ogino K, Makiyama Y, Nakagawa S, Kurimoto M, Yoshimura N. Wide-Field fundus autofluorescence imaging of retinitis pigmentosa. Ophthalmology. 2013;120:1827-1834.
  52. Sakai R, Wang W, Yamaguchi N, Tamura H, Goto R, Kawachi I. The impact of Japan's 2004 postgraduate training program on intra-prefectural distribution of pediatricians in Japan. PLoS One. 2013;8:e77045.
  53. Ellabban AA, Tsujikawa A, Ooto S, Yamashiro K, Oishi A, Nakata I, Miyake M, Akagi-Kurashige Y, Ueda-Arakawa N, Arichika S, Yoshitake S, Takahashi A, Yoshimura N. Focal choroidal excavation in eyes with central serous chorioretinopathy.Am J Ophthalmol. 2013;156:673-683.
  54. Muraoka Y, Tsujikawa A, Kumagai K, Akiba M, Ogino K, Murakami T, Akagi-Kurashige Y, Miyamoto K, Yoshimura N. Age- and hypertension-dependent changes in retinal vessel diameter and wall thickness: An optical coherence tomography study. Am J Ophthalmol. 2013;156:706-714.
  55. Oishi A, Kojima H, Mandai M, Honda S, Matsuoka T, Oh H, Kita M, Nagai T, Fujihara M, Bessho N, Uenishi M, Kurimoto Y, Negi A. Comparison of the effect of ranibizumab and verteporfin for polypoidal choroidal vasculopathy: 12-month LAPTOP study results. Am J Ophthalmol. 2013;156:644-651.
  56. Hirose F, Hata M, Ito S, Matsuki T, Kurimoto Y. Light-dark changes in iris thickness and anterior chamber angle width in eyes with occludable angles. Graefe’s Arch Clin Exp Ophthalmol. 2013;251:2395-2402.
  57. Nakata I, Yamashiro K, Nakanishi H, Akagi-Kurashige Y, Miyake M, Tsujikawa A, Matsuda F, Yoshimura N. The Nagahama Cohort Research Group. Prevalence and characteristics of age-related macular degeneration in the Japanese population: The Nagahama Study. Am J Ophthalmol. 2013;156:1002-1009.
  58. Kimura Y, Hangai M, Matsumoto A, Akagi T, Ikeda HO, Ohkubo S, Sugiyama K, Iwase A, Araie M, Yoshimura N. Macular structure parameters as an automated indicator of paracentral scotoma in early glaucoma. Am J Ophthalmol. 2013;156:907-917.
  59. Uji A, Ooto S, Hangai M, Arichika S, Yoshimura N. Image quality improvement in adaptive optics scanning laser ophthalmoscopy assisted capillary visualization using Bspline-based elastic image registration. PLoS One. 2013;8:e80106.
  60. Oishi M, Yamashiro K, Miyake M, Akagi-Kurashige Y, Kumagai K, Nakata I, Nakanishi H, Yoshikawa M, Oishi A, Gotoh N, Tsujikawa A; Nagahama Study Group, Yamada R, Matsuda F, Yoshimura N. Association between ZIC2, RASGRF1, and SHISA6 genes and high myopia in Japanese subjects. Invest Ophthalmol Vis Sci. 2013;54:7492-7497.
  61. Makiyama Y, Ooto S, Hangai M, Takayama K, Uji A, Oishi A, Ogino K, Nakagawa S, Yoshimura N. Macular cone abnormalities in retinitis pigmentosa with preserved central vision using adaptive optics scanning laser ophthalmoscopy. PLoS One. 2013;8:e79447.
  62. Murakami T, Uji A, Ogino K, Unoki N, Horii T, Yoshitake S, Nishijima K, Yoshimura N. Association between perifoveal hyperfluorescence and serous retinal detachment in diabetic macular edema. Ophthalmology. 2013;120:2596-2603.
  63. Ooto S, Ellabban AA, Ueda-Arakawa N, Oishi A, Tamura H, Yamashiro K, Tsujikawa A, Yoshimura N. Reduction of retinal sensitivity in eyes with reticular pseudodrusen. Am J Ophthalmol. 2013;156:1184-1191.
  64. Khor CC, Miyake M, Chen LJ, Shi Y, Barathi VA, Qiao F, Nakata I, Yamashiro K, Zhou X, Tam PO, Cheng CY, Tai ES, Vithana EN, Aung T, Teo YY, Wong TY, Moriyama M, Ohno-Matsui K, Mochizuki M, Matsuda F; Nagahama Study Group, Yong RY, Yap EP, Yang Z, Pang CP, Saw SM, Yoshimura N. Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia. Hum Mol Genet. 2013;22:5288-5294.